{"symbol":"CNOT1","synonyms":["NOT1H","AD-005","CDC39","NOT1"],"name":"CCR4-NOT transcription complex, subunit 1","description":"Enables armadillo repeat domain binding activity; molecular adaptor activity; and nuclear receptor binding activity. Contributes to poly(A)-specific ribonuclease activity. Involved in several processes, including negative regulation of intracellular signal transduction; positive regulation of cytoplasmic mRNA processing body assembly; and regulation of gene expression. Located in P-body and cytosol. Part of CCR4-NOT complex. Implicated in Vissers-Bodmer syndrome and holoprosencephaly 12. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":23019,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23019","proteins":[{"symbol":"CNOT1_HUMAN","href":"/api/1.0/protein/CNOT1_HUMAN"}],"hgncRootFamilies":[]}