{"symbol":"CNOT7","synonyms":["HCAF-1"],"name":"CCR4-NOT transcription complex, subunit 7","description":"The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]","ncbiEntrezGeneId":29883,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/29883","proteins":[{"symbol":"CNOT7_HUMAN","href":"/api/1.0/protein/CNOT7_HUMAN"}],"hgncRootFamilies":[]}