{"symbol":"COMMD1","synonyms":["C2ORF5","MURR1"],"name":"copper metabolism (Murr1) domain containing 1","description":"Enables several functions, including phosphatidylinositol-3,4-bisphosphate binding activity; phospholipid binding activity; and protein homodimerization activity. Involved in several processes, including Golgi to plasma membrane transport; negative regulation of protein localization to cell surface; and regulation of protein metabolic process. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity. Located in cytosol; endosome; and nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":150684,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/150684","proteins":[{"symbol":"COMD1_HUMAN","href":"/api/1.0/protein/COMD1_HUMAN"}],"hgncRootFamilies":[]}