{"symbol":"CORIN","synonyms":["TMPRSS10","ATC2","CRN","PEE5","Lrp4"],"name":"corin, serine peptidase","description":"This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]","ncbiEntrezGeneId":10699,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10699","proteins":[{"symbol":"CORIN_HUMAN","href":"/api/1.0/protein/CORIN_HUMAN"}],"hgncRootFamilies":[{"name":"Proteases, serine (PRSS)","href":"/api/1.0/gene_family/Proteases%2C+serine+%28PRSS%29"}]}