{"symbol":"CORO7","synonyms":["CRN7","0610011B16RIK"],"name":"coronin 7","description":"This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants; some of which form read-through transcripts with a neighboring gene. [provided by RefSeq, Dec 2016]","ncbiEntrezGeneId":79585,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79585","proteins":[{"symbol":"CORO7_HUMAN","href":"/api/1.0/protein/CORO7_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}