{"symbol":"CPN1","synonyms":["CPN","SCPN"],"name":"carboxypeptidase N, polypeptide 1","description":"Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1369,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1369","proteins":[{"symbol":"CBPN_HUMAN","href":"/api/1.0/protein/CBPN_HUMAN"}],"hgncRootFamilies":[]}