{"symbol":"CPSF1","synonyms":["HSU37012","P/CL.18","CPSF160"],"name":"cleavage and polyadenylation specific factor 1, 160kDa","description":"Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":29894,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/29894","proteins":[{"symbol":"CPSF1_HUMAN","href":"/api/1.0/protein/CPSF1_HUMAN"}],"hgncRootFamilies":[]}