{"symbol":"CPT1A","synonyms":["CPT1","CPT1-L","L-CPT1"],"name":"carnitine palmitoyltransferase 1A (liver)","description":"The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1374,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1374","proteins":[{"symbol":"CPT1A_HUMAN","href":"/api/1.0/protein/CPT1A_HUMAN"}],"hgncRootFamilies":[]}