{"symbol":"CRAT","synonyms":["NBIA8","CAT1"],"name":"carnitine O-acetyltransferase","description":"This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments. [provided by RefSeq, Oct 2016]","ncbiEntrezGeneId":1384,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1384","proteins":[{"symbol":"CACP_HUMAN","href":"/api/1.0/protein/CACP_HUMAN"}],"hgncRootFamilies":[]}