{"symbol":"CRKL","synonyms":[],"name":"v-crk avian sarcoma virus CT10 oncogene homolog-like","description":"This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]","ncbiEntrezGeneId":1399,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1399","proteins":[{"symbol":"CRKL_HUMAN","href":"/api/1.0/protein/CRKL_HUMAN"}],"hgncRootFamilies":[{"name":"SH2 domain containing","href":"/api/1.0/gene_family/SH2+domain+containing"}]}