{"symbol":"CRLF1","synonyms":["CISS1","CLF-1","ZCYTOR5","NR6","CISS"],"name":"cytokine receptor-like factor 1","description":"This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":9244,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9244","proteins":[{"symbol":"CRLF1_HUMAN","href":"/api/1.0/protein/CRLF1_HUMAN"}],"hgncRootFamilies":[{"name":"Fibronectin type III domain containing","href":"/api/1.0/gene_family/Fibronectin+type+III+domain+containing"}]}