{"symbol":"CRTC3","synonyms":["TORC-3","TORC3"],"name":"CREB regulated transcription coactivator 3","description":"This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]","ncbiEntrezGeneId":64784,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64784","proteins":[{"symbol":"CRTC3_HUMAN","href":"/api/1.0/protein/CRTC3_HUMAN"}],"hgncRootFamilies":[]}