{"symbol":"CRYM","synonyms":["DFNA40","THBP"],"name":"crystallin, mu","description":"Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":1428,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1428","proteins":[{"symbol":"CRYM_HUMAN","href":"/api/1.0/protein/CRYM_HUMAN"}],"hgncRootFamilies":[]}