{"symbol":"CTDSP1","synonyms":["NIF3","NLI-IF","NLIIF"],"name":"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1","description":"This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":58190,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/58190","proteins":[{"symbol":"CTDS1_HUMAN","href":"/api/1.0/protein/CTDS1_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphatases","href":"/api/1.0/gene_family/Phosphatases"}]}