{"symbol":"CTSA","synonyms":["GLB2","GSL","PPCA","NGBE","PPGB"],"name":"cathepsin A","description":"This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015]","ncbiEntrezGeneId":5476,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5476","proteins":[{"symbol":"PPGB_HUMAN","href":"/api/1.0/protein/PPGB_HUMAN"}],"hgncRootFamilies":[{"name":"Cathepsins (CTS)","href":"/api/1.0/gene_family/Cathepsins+%28CTS%29"}]}