{"symbol":"CUL5","synonyms":["VACM-1","CUL-5","VACM1"],"name":"cullin 5","description":"Enables ubiquitin ligase complex scaffold activity and ubiquitin protein ligase binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein K11-linked ubiquitination. Located in site of DNA damage. Part of Cul5-RING ubiquitin ligase complex. Is active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":8065,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8065","proteins":[{"symbol":"CUL5_HUMAN","href":"/api/1.0/protein/CUL5_HUMAN"}],"hgncRootFamilies":[]}