{"symbol":"DCAF11","synonyms":["WDR23","GL014","PRO2389"],"name":"DDB1 and CUL4 associated factor 11","description":"This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]","ncbiEntrezGeneId":80344,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/80344","proteins":[{"symbol":"DCA11_HUMAN","href":"/api/1.0/protein/DCA11_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"},{"name":"DDB1 and CUL4 associated factors (DCAF)","href":"/api/1.0/gene_family/DDB1+and+CUL4+associated+factors+%28DCAF%29"}]}