{"symbol":"DCD","synonyms":["DCD-1","AIDD"],"name":"dermcidin","description":"This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]","ncbiEntrezGeneId":117159,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/117159","proteins":[{"symbol":"DCD_HUMAN","href":"/api/1.0/protein/DCD_HUMAN"}],"hgncRootFamilies":[]}