{"symbol":"DCXR","synonyms":["HCR2","HCRII","PNTSU","KIDCR","DCR","P34H","XR","SDR20C1"],"name":"dicarbonyl/L-xylulose reductase","description":"The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]","ncbiEntrezGeneId":51181,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51181","proteins":[{"symbol":"DCXR_HUMAN","href":"/api/1.0/protein/DCXR_HUMAN"}],"hgncRootFamilies":[{"name":"Short chain dehydrogenase/reductase superfamily (SDR)","href":"/api/1.0/gene_family/Short+chain+dehydrogenase%24slash%24reductase+superfamily+%28SDR%29"}]}