{"symbol":"DDOST","synonyms":["GATD6","CDG1R","WBP1","OST","OKSWCL45","AGER1","OST48"],"name":"dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)","description":"This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1650,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1650","proteins":[{"symbol":"OST48_HUMAN","href":"/api/1.0/protein/OST48_HUMAN"}],"hgncRootFamilies":[{"name":"Oligosaccharyltransferase complex","href":"/api/1.0/gene_family/Oligosaccharyltransferase+complex"}]}