{"symbol":"DEFB105A","synonyms":["DEFB-5","DEFB105"],"name":"defensin, beta 105A","description":"Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]","ncbiEntrezGeneId":245908,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/245908","proteins":[{"symbol":"D105A_HUMAN","href":"/api/1.0/protein/D105A_HUMAN"}],"hgncRootFamilies":[{"name":"Defensins","href":"/api/1.0/gene_family/Defensins"}]}