{"symbol":"DEFB106A","synonyms":["DEFB106","DEFB-6"],"name":"defensin, beta 106A","description":"Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]","ncbiEntrezGeneId":245909,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/245909","proteins":[{"symbol":"D106A_HUMAN","href":"/api/1.0/protein/D106A_HUMAN"}],"hgncRootFamilies":[{"name":"Defensins","href":"/api/1.0/gene_family/Defensins"}]}