{"symbol":"DEFB118","synonyms":["C20ORF63","ESC42","DEFB-18","ESP13.6"],"name":"defensin, beta 118","description":"This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity against E. coli. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Nov 2014]","ncbiEntrezGeneId":117285,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/117285","proteins":[{"symbol":"DB118_HUMAN","href":"/api/1.0/protein/DB118_HUMAN"}],"hgncRootFamilies":[{"name":"Defensins","href":"/api/1.0/gene_family/Defensins"}]}