{"symbol":"DHRS9","synonyms":["RDHTBE","3ALPHA-HSD","RETSDR8","RDH-E2","SDR9C4","RDHL","RDH-TBE","RDH15"],"name":"dehydrogenase/reductase (SDR family) member 9","description":"This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]","ncbiEntrezGeneId":10170,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10170","proteins":[{"symbol":"DHRS9_HUMAN","href":"/api/1.0/protein/DHRS9_HUMAN"}],"hgncRootFamilies":[{"name":"Short chain dehydrogenase/reductase superfamily (SDR)","href":"/api/1.0/gene_family/Short+chain+dehydrogenase%24slash%24reductase+superfamily+%28SDR%29"}]}