{"symbol":"DICER1","synonyms":["K12H4.8-LIKE","DICER","HERNA","MNG1","DICER1E","RMSE2"],"name":"dicer 1, ribonuclease type III","description":"This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. This protein also acts as a strong antiviral agent with activity against RNA viruses, including the Zika and SARS-CoV-2 viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2021]","ncbiEntrezGeneId":23405,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23405","proteins":[{"symbol":"DICER_HUMAN","href":"/api/1.0/protein/DICER_HUMAN"}],"hgncRootFamilies":[]}