{"symbol":"DIS3","synonyms":["RRP44","2810028N01RIK","EXOSC11","KIAA1008","DIS3P"],"name":"DIS3 exosome endoribonuclease and 3\u0027-5\u0027 exoribonuclease","description":"Enables 3\u0027-5\u0027-RNA exonuclease activity; endonuclease activity; and guanyl-nucleotide exchange factor activity. Involved in CUT catabolic process; RNA processing; and rRNA catabolic process. Located in cytosol and nucleoplasm. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":22894,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/22894","proteins":[{"symbol":"RRP44_HUMAN","href":"/api/1.0/protein/RRP44_HUMAN"}],"hgncRootFamilies":[{"name":"Exosome components (EXOSC)","href":"/api/1.0/gene_family/Exosome+components+%28EXOSC%29"}]}