{"symbol":"DMAP1","synonyms":["SWC4","MEAF2","DNMAP1","EAF2","DNMTAP1"],"name":"DNA methyltransferase 1 associated protein 1","description":"This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":55929,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55929","proteins":[{"symbol":"DMAP1_HUMAN","href":"/api/1.0/protein/DMAP1_HUMAN"}],"hgncRootFamilies":[{"name":"SANT/Myb domain containing","href":"/api/1.0/gene_family/SANT%24slash%24Myb+domain+containing"}]}