{"symbol":"DMRT1","synonyms":["DMT1","CT154"],"name":"doublesex and mab-3 related transcription factor 1","description":"This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1761,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1761","proteins":[{"symbol":"DMRT1_HUMAN","href":"/api/1.0/protein/DMRT1_HUMAN"}],"hgncRootFamilies":[]}