{"symbol":"DNAH5","synonyms":["PCD","HL1","KTGNR","DNAHC5","CILD3"],"name":"dynein, axonemal, heavy chain 5","description":"This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":1767,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1767","proteins":[{"symbol":"DYH5_HUMAN","href":"/api/1.0/protein/DYH5_HUMAN"}],"hgncRootFamilies":[{"name":"Dyneins","href":"/api/1.0/gene_family/Dyneins"}]}