{"symbol":"DNAJB1","synonyms":["HDJ1","HSPF1","RSPH16B","Hsp40","SIS1"],"name":"DnaJ (Hsp40) homolog, subfamily B, member 1","description":"This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the \u0027J-domain\u0027 and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]","ncbiEntrezGeneId":3337,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3337","proteins":[{"symbol":"DNJB1_HUMAN","href":"/api/1.0/protein/DNJB1_HUMAN"}],"hgncRootFamilies":[{"name":"Heat shock proteins","href":"/api/1.0/gene_family/Heat+shock+proteins"}]}