{"symbol":"DNAJB5","synonyms":["HSC40"],"name":"DnaJ (Hsp40) homolog, subfamily B, member 5","description":"This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy. [provided by RefSeq, Mar 2017]","ncbiEntrezGeneId":25822,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/25822","proteins":[{"symbol":"DNJB5_HUMAN","href":"/api/1.0/protein/DNJB5_HUMAN"}],"hgncRootFamilies":[{"name":"Heat shock proteins","href":"/api/1.0/gene_family/Heat+shock+proteins"}]}