{"symbol":"DNAJC24","synonyms":["JJJ3","ZCSL3","DPH4"],"name":"DnaJ (Hsp40) homolog, subfamily C, member 24","description":"Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":120526,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/120526","proteins":[{"symbol":"DJC24_HUMAN","href":"/api/1.0/protein/DJC24_HUMAN"}],"hgncRootFamilies":[{"name":"Heat shock proteins","href":"/api/1.0/gene_family/Heat+shock+proteins"}]}