{"symbol":"DOT1L","synonyms":["KMT4","DOT1"],"name":"DOT1-like histone H3K79 methyltransferase","description":"The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]","ncbiEntrezGeneId":84444,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84444","proteins":[{"symbol":"DOT1L_HUMAN","href":"/api/1.0/protein/DOT1L_HUMAN"}],"hgncRootFamilies":[{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}