{"symbol":"DPP3","synonyms":["DPPIII"],"name":"dipeptidyl-peptidase 3","description":"This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":10072,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10072","proteins":[{"symbol":"DPP3_HUMAN","href":"/api/1.0/protein/DPP3_HUMAN"}],"hgncRootFamilies":[]}