{"symbol":"DRD2","synonyms":["D2R","D2DR"],"name":"dopamine receptor D2","description":"This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1813,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1813","proteins":[{"symbol":"DRD2_HUMAN","href":"/api/1.0/protein/DRD2_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}