{"symbol":"DRD4","synonyms":["D4DR"],"name":"dopamine receptor D4","description":"This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1815,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1815","proteins":[{"symbol":"DRD4_HUMAN","href":"/api/1.0/protein/DRD4_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}