{"symbol":"DSG2","synonyms":["CDHF5","ARVD10","CMD1BB","HDGC","ARVC10"],"name":"desmoglein 2","description":"This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":1829,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1829","proteins":[{"symbol":"DSG2_HUMAN","href":"/api/1.0/protein/DSG2_HUMAN"}],"hgncRootFamilies":[{"name":"Cadherins","href":"/api/1.0/gene_family/Cadherins"}]}