{"symbol":"DTL","synonyms":["CDT2","DCAF2","L2DTL"],"name":"denticleless E3 ubiquitin protein ligase homolog (Drosophila)","description":"Contributes to ubiquitin-protein transferase activity. Involved in several processes, including protein ubiquitination; regulation of G2/M transition of mitotic cell cycle; and translesion synthesis. Located in centrosome; cytosol; and nuclear lumen. Part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":51514,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51514","proteins":[{"symbol":"DTL_HUMAN","href":"/api/1.0/protein/DTL_HUMAN"}],"hgncRootFamilies":[{"name":"DDB1 and CUL4 associated factors (DCAF)","href":"/api/1.0/gene_family/DDB1+and+CUL4+associated+factors+%28DCAF%29"},{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}