{"symbol":"DUOX2","synonyms":["NOXEF2","LNOX2","THOX2","P138-TOX","TDH6"],"name":"dual oxidase 2","description":"The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":50506,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/50506","proteins":[{"symbol":"DUOX2_HUMAN","href":"/api/1.0/protein/DUOX2_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}