{"symbol":"DUS2","synonyms":["URLC8","SMM1","DUS2L"],"name":"dihydrouridine synthase 2","description":"This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]","ncbiEntrezGeneId":54920,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54920","proteins":[{"symbol":"DUS2L_HUMAN","href":"/api/1.0/protein/DUS2L_HUMAN"}],"hgncRootFamilies":[]}