{"symbol":"DUSP22","synonyms":["LMWDSP2","VHX","JKAP","LMW-DSP2","JSP-1","JSP1","MKP-X"],"name":"dual specificity phosphatase 22","description":"Enables phosphoprotein phosphatase activity; protein tyrosine kinase binding activity; and protein tyrosine kinase inhibitor activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of T cell receptor signaling pathway; and negative regulation of focal adhesion assembly. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm; leading edge of lamellipodium; and plasma membrane. Part of filamentous actin. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":56940,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/56940","proteins":[{"symbol":"DUS22_HUMAN","href":"/api/1.0/protein/DUS22_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphatases","href":"/api/1.0/gene_family/Phosphatases"}]}