{"symbol":"ECSCR","synonyms":["ECSM2"],"name":"endothelial cell surface expressed chemotaxis and apoptosis regulator","description":"The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]","ncbiEntrezGeneId":641700,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/641700","proteins":[{"symbol":"ECSCR_HUMAN","href":"/api/1.0/protein/ECSCR_HUMAN"}],"hgncRootFamilies":[]}