{"symbol":"EDEM3","synonyms":["C1ORF22"],"name":"ER degradation enhancer, mannosidase alpha-like 3","description":"Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":80267,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/80267","proteins":[{"symbol":"EDEM3_HUMAN","href":"/api/1.0/protein/EDEM3_HUMAN"}],"hgncRootFamilies":[]}