{"symbol":"EGLN3","synonyms":["HIFPH3","HIFP4H3","PHD3"],"name":"egl-9 family hypoxia-inducible factor 3","description":"Enables peptidyl-proline 4-dioxygenase activity. Involved in several processes, including positive regulation of cysteine-type endopeptidase activity; protein hydroxylation; and response to hypoxia. Located in cytosol and nucleus. Implicated in renal cell carcinoma. Biomarker of clear cell renal cell carcinoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":112399,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/112399","proteins":[{"symbol":"EGLN3_HUMAN","href":"/api/1.0/protein/EGLN3_HUMAN"}],"hgncRootFamilies":[]}