{"symbol":"EHD1","synonyms":["PAST1","H-PAST","HPAST1","PAST"],"name":"EH-domain containing 1","description":"This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":10938,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10938","proteins":[{"symbol":"EHD1_HUMAN","href":"/api/1.0/protein/EHD1_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}