{"symbol":"EHD2","synonyms":["PAST2"],"name":"EH-domain containing 2","description":"This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":30846,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/30846","proteins":[{"symbol":"EHD2_HUMAN","href":"/api/1.0/protein/EHD2_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}