{"symbol":"EIF2A","synonyms":["CDA02","MST089","MSTP004","MSTP089"],"name":"eukaryotic translation initiation factor 2A, 65kDa","description":"This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly(U)-directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":83939,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/83939","proteins":[{"symbol":"EIF2A_HUMAN","href":"/api/1.0/protein/EIF2A_HUMAN"}],"hgncRootFamilies":[]}