{"symbol":"EIF4E2","synonyms":["IF4E","4EHP","4E-LP","EIF4EL3","h4EHP"],"name":"eukaryotic translation initiation factor 4E family member 2","description":"Enables RNA 7-methylguanosine cap binding activity; mRNA cap binding activity; and ubiquitin protein ligase binding activity. Involved in negative regulation of translational initiation; negative regulation of type I interferon-mediated signaling pathway; and rescue of stalled ribosome. Acts upstream of with a positive effect on miRNA-mediated gene silencing by inhibition of translation. Acts upstream of or within negative regulation of translation. Located in P-body. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":9470,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9470","proteins":[{"symbol":"IF4E2_HUMAN","href":"/api/1.0/protein/IF4E2_HUMAN"}],"hgncRootFamilies":[]}