{"symbol":"ENC1","synonyms":["KLHL35","TP53I10","KLHL37","NRPB","PIG10","CCL28","ENC-1"],"name":"ectodermal-neural cortex 1 (with BTB domain)","description":"This gene encodes a member of the kelch-related family of actin-binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":8507,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8507","proteins":[{"symbol":"ENC1_HUMAN","href":"/api/1.0/protein/ENC1_HUMAN"}],"hgncRootFamilies":[{"name":"BTB (POZ) domain containing (BTBD)","href":"/api/1.0/gene_family/BTB+%28POZ%29+domain+containing+%28BTBD%29"},{"name":"Kelch-like (KLHL)","href":"/api/1.0/gene_family/Kelch-like+%28KLHL%29"}]}