{"symbol":"ENTPD7","synonyms":["LALP1"],"name":"ectonucleoside triphosphate diphosphohydrolase 7","description":"This gene encodes a purine-converting ectoenzyme which belongs to the ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) family. The encoded protein hydrolyzes extracellular nucleoside triphosphates (UTP, GTP, and CTP) to nucleoside monophosphates as part of a purinergic signaling pathway. It contains two transmembrane domains at the N- and C-termini and a large, hydrophobic catalytic domain located in between. This gene affects oxidative stress as well as DNA damage and is a mediator of senescence. [provided by RefSeq, Mar 2017]","ncbiEntrezGeneId":57089,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57089","proteins":[{"symbol":"ENTP7_HUMAN","href":"/api/1.0/protein/ENTP7_HUMAN"}],"hgncRootFamilies":[]}